Effects of ultraviolet light on mouse L cells.

Cover of: Effects of ultraviolet light on mouse L cells. | Masaharu Domon

Published in [Toronto] .

Written in English

Read online


  • Cell division (Biology),
  • Cytology,
  • Mice,
  • Ultra-violet rays -- Physiological effect

Edition Notes

Book details

ContributionsToronto, Ont. University.
The Physical Object
Pagination105 leaves.
Number of Pages105
ID Numbers
Open LibraryOL20174868M

Download Effects of ultraviolet light on mouse L cells.

Damage produced by low exposures of ultraviolet-light (UV) irradiation exerts a specific effect on mouse L cells during their passage through their first S phase after irradiation. Previous results showed that irradiation of a synchronized cell population occupying late G 1 to early S phase wor$\ {\rm ergs}/{\rm mm}^{2}$ of UV Cited by: To evaluate the etiologic role of ultraviolet (UV) radiation in acquired dermal melanocytosis (ADM), we investigated the effects of UVA and UVB irradiation on the development and differentiation of melanocytes in primary cultures of mouse neural crest cells (NCC) by counting the numbers of cells positive for KIT (the receptor for stem cell factor) and for the L ‐3,4‐dihydroxyphenylalanine Cited by: 1.

Radiat Res. Nov;40(2) Ultraviolet-light irradiation of mouse L cells: effects on cells in the DNA synthesis phase. Domon M, Rauth by:   Ultraviolet-light irradiation of mouse L cells: effects on cells in the DNA synthesis phase.

(PMID) Abstract Citations; Related Articles; Data; BioEntities; External Links ' ' Domon M, ' ' Rauth AM Radiation Research [01 Nov40(2)] Type: Cited by:   Ultraviolet-Light Irradiation of Mouse L Cells: Effects on Cells in the DNA Synthesis PhaseCited by: 1.

Exp Cell Res. Jan; Effects of ultraviolet light on multiplication and deoxyribonucleic acid synthesis in cultures of L strain mouse cells. The effect of in vivo ultraviolet−B radiation to the activity of mouse macrophage measured by NO2− production Comparison with TNF alpha (in Japanese) January Inflammation and.

Radiat Res. Jul;47(1) A comparison of the sensitivity to ultraviolet light of mouse L cells and mouse bone marrow cells assayed in vitro. We then examined the effects of UV light on KIT-positive cell lines derived from mouse NCC cultures.

Irradiation with UVA but not with UVB inhibited the tyrosinase activity in a tyrosinase-positive cell line (NCCmelan5). Tyrosinase activity in the cells was markedly enhanced by treatment with alpha-melanocyte-stimulating hormone (alpha-MSH), but that stimulation was inhibited by UVA or by UVB. Basically, UV kills cells because of the accumulation of DNA damage.

A gene product, called p53, is one of the responsible parties for slowing the cell cycle and checking for damage. If the damage. UV-reactivation, virus production and mutagenesis of SV40 in VU-irradiated monkey kidney cells.

Mutat Res. Jun; 71 (1)– Cornelis JJ, Su ZZ, Ward DC, Rommelaere J. Indirect induction of mutagenesis of intact parvovirus H-1 in mammalian cells treated with UV light or with UV-irradiated H-1 or simian virus thermostat (Lauda).

Immediately after near ultraviolet and visible light (VL) exposure, the cells were thoroughly washed with medium and kept singly or in groups of 10 in Syracuse watch glasses together with Effects of ultraviolet light on mouse L cells.

book organisms. Cells treated identically but without VL exposure were used as controls. The Effect of Ultraviolet Light on Cell Viability, DNA Damage and Repair in Hutchinson-Gilford Progeria Syndrome and BJ Fibroblasts A thesis presented to The faculty of the Department of Biological Sciences East Tennessee State University In partial fulfillment of the requirements for the.

Start studying Ultraviolet light: Lethal Effects. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Start a free trial of Quizlet Plus by Thanksgiving |. A quick primer on UV light: UV light comes primarily from the sun, but there are also man-made sources of UV light, including tanning beds and the currently buzzed-about UV disinfection lamps.

Nowadays, UV light is an important treatment option for several skin diseases including psoriasis, atopic dermatitis, morphea, scleroderma, vitiligo, and mycosis fungoides. 5 A mood‐enhancing effect of UV light has also been reported. This effect might be accomplished via two target organs working as receptors for UV light: that is skin.

Final Report}, author = {Bernheim, F and Wilbur, K M}, abstractNote = {Results are summarized from a series of studies on the effects of ultraviolet and ionizing radiation on the oxidation of cell lipids.

It was shown that both in vitro and in vivo radiation produced oxidation products of lipids that inhibited the activity of certain oxidative enzymes, depolymerized desoxyribonucleoprotein, inhibited the division of marine eggs, and retarded. Abstract. Ultraviolet light (UV) has been extensively used as a damage inducing agent in mammalian cells in in vitro cell cultures.

The wavelengths studied have been primarily in the range of nm where deoxyribonucleic acid (DNA) absorbs most strongly. Hi there, UV light is cytotoxic and directly interacts with DNA in cells to cause damage that may include apoptosis or mutagenesis.

This damage is proportional to the intensity and duration of. Exposure to the solar ultraviolet spectrum that penetrates the Earth's stratosphere (UVA and UVB) causes cellular DNA damage within skin cells. This damage is elicited directly through absorption of energy (UVB), and indirectly through intermediates such as sensitizer radicals and reactive oxygen species (UVA).

DNA damage is detected as strand breaks or as base lesions, the most common. Original Article Effects of Ultraviolet B Light on Cutaneous Immune Responses of Humans with Deeply Pigmented Skin Martin Vermeer, 1 George J Schmieder, 2 Takeshi Yoshikawa, 1 Jan-Willem van den Berg, 1 Michael S Metzman, J Richard Taylor, 2 3 J Wayne Streilein, 1 1 Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida, U.S.A.

Most ultraviolet (UV) light from the Sun is blocked by the atmosphere before making it to the surface, but the American Cancer Society points out that UV light is still the main cause of the damaging effects of sunlight on human skin.

In most circumstances, you’ll hear a lot more about the dangers of UV light than any positive effects it has; however, there are both advantages and. The human and mouse retina contain a different complement of light-sensitive visual pigments.

A) The human retina contains rods and three cone classes, maximally sensitive to red, green and blue light. B) By contrast, the mouse retina is rod dominated (97% of photoreceptors) and contains cone opsins maximally sensitive to ultraviolet and green. A new sci-fi like treatment uses ultraviolet light to kill targeted cancer cells in a non invasive method that could be an option for hard to treat tumors.

UV radiation can often cause DNA mutations and damage cells. It was tested how the time of exposure to UV light is correlated to the reversion on the mutation of the trp allele on yeast cells, as well if it has any effect on the number of yeast.

UV light: Lethal Effects •Break up into 4 groups •Group 1: S. epidermis 10sec, 20 sec, 40sec, 80 sec •Group 2: S. epidermis min, 5 min, 10 min 10min* •Group 3: B. megaterium 1min, 2min, 4 min, 8 min •Group 4: B. megaterium 15 min, 30 min, 60 min 60 min* •8 plates/group: repeat experiment twice.

Ultraviolet (UV) radiation is known to inhibit cell growth and induce gene damage (1). For these reasons, UV radiation is used as a method to sterilize surgical instruments because it kills the bacteria present and disrupts bacterial reproduction (2).

Jagger, J. Effects and mechanisms of near-UV (UV-A) radiation actions on cells. Sublethal effects. Abstracts, Fifth Annual Meeting of the American Society for Photobiology, San Juan,p. UV exposure is known to induce T Reg activation [9,24], which is critical for preventing aberrant T cell activation, so we next examined changes in T Reg populations following UVB exposure.

Interestingly, BALB/c but not NZM mice demonstrated a significant increase in T Reg cell numbers 24hrs post UVB treatment (Fig. 3A and B). Strikingly, a significant increase in activated, CD69 + T Reg cells. To understand the mutagenic effects of UV irradiation on a molecular level, it is a well-known fact that short wavelength rays (such as UV) interact with water molecules in the cell to produce free radicals (-OH).

Such free radicals lack one or more electrons and attack other molecules such as cell proteins or DNA to rob them of electrons. the harmful effects of ultraviolet light on various organisms. Bac- teria, for example, are readily killed by the so-called ^'middle ultra- violet ^\ that is, by radiations of wave lengths between and m/i ^ ; plants are rather generally harmed by wave lengths shorter than m/x^; and animals, including man, may suffer from serious burns.

primary lethal effect of UV light due to. mutagenic properties. UV radiation at nm. results in cell death. killing properties of UV light. time of exposure presence of materials that block radiation from reaching cell. what can block UV radiation. plastic/lenses. Exposure to UV-B light prevented multiple sclerosis (MS)-like symptoms in a mouse model regardless of the presence of vitamin D or the vitamin D receptor, a new study discovered.

The study, “UV. Spores survive to regenerate later and only the vegative portion of these cells are killed by UV light. What does the SOS system do. enzymatically removes the damaged dimer and inserts new pyrimidines. Ultraviolet Light: Lethal Effects. 13 terms.

Lab 10 Part 2 - Effect of UV Light. 55 terms. Lab exam #2. 10 terms. Micro Lab # 31 (33) OTHER. What Are the Effects of Ultraviolet Light on Bacteria Mortality Biology Projects, Biology Science Fair Project Ideas, Biology Topics for CBSE School,ICSE Biology Experiments for Kids and also for Middle school, Elementary School for class 5th Grade,6th,7th,8th,9th 10th,11th, 12th Grade and High School, MSC and College Students.

Start studying Exercise Ultraviolet Light: Lethal Effects. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Patients of Hutchinson-Gilford Progeria Syndrome (HGPS) display a rate of aging up to ten times that of normal human populations.

It might be expected that HGPS cells would have a decreased ability to repair DNA damage through the cell cycle as compared to normal cells such as those of the BJ cell line since DNA damage accumulation is a hallmark phenotype of aging.

On earth. Late cornified envelope family in differentiating epithelia--response to calcium and ultraviolet irradiation J Invest Dermatol. May;(5) doi: /jXx. To avoid a heating effect on the cell samples, the visible laser.

Post UV light deployment, only % of surfaces tested positive for the DNA tracer after 48 hours. Book. Full-text. Ultraviolet (UV) is a form of electromagnetic radiation with wavelength from 10 (with a corresponding frequency around 30 PHz) to nm ( THz), shorter than that of visible light, but longer than radiation is present in sunlight, and constitutes about 10% of the total electromagnetic radiation output from the is also produced by electric arcs and specialized lights, such.

Global atmospheric changes such as depletion of ozone in the stratosphere are thought to lead to increased levels of ultraviolet radiation on earth. This can have adverse effects on human health, and long-term effects of ultraviolet light on the eye are of increasing concern.Technical Report: THE EFFECTS OF ULTRAVIOLET LIGHT AND GAMMA RAYS ON CELL LIPIDS AND THE PHYSIOLOGICAL ACTION OF IRRADIATED LIPIDS.

Progress Report, September 1, to Aug   Ultraviolet light boosts cancer treatment By Nic Fleming, Science Correspondent 30 October • am Ultraviolet light can be used to maximise the impact and minimise the side effects .

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